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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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Drug ID
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DrugBank ID
KEGG ID
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ADR Ontology
ADR Term
Jaundice
ADR ID
BADD_A02422
ADR Hierarchy
01
Blood and lymphatic system disorders
01.06
Haemolyses and related conditions
01.06.04
Haemolyses NEC
01.06.04.004
Jaundice
09
Hepatobiliary disorders
09.01
Hepatic and hepatobiliary disorders
09.01.01
Cholestasis and jaundice
09.01.01.004
Jaundice
23
Skin and subcutaneous tissue disorders
23.03
Epidermal and dermal conditions
23.03.03
Dermal and epidermal conditions NEC
23.03.03.030
Jaundice
Description
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction. [MeSH]
MedDRA Code
10023126
MeSH ID
D007565
;
D007565
;
D007565
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Icterus | Jaundice | Jaundice (excl neonatal) | Jaundice NOS | Jaundice, unspecified, not of newborn | Subicteric | Jaundice, Hemolytic | Hemolytic Jaundice | Hemolytic Jaundices | Jaundices, Hemolytic
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Alanine aminotransferase 1
P24298
Not Available
Alkaline phosphatase, tissue-nonspecific isozyme
P05186
T09538
Glutathione hydrolase 7
Q9UJ14
T25122
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00510
Cloxacillin
-
-
BADD_D00511
Clozapine
-
-
BADD_D00512
Cobicistat
-
-
BADD_D00535
Crizotinib
-
-
BADD_D00545
Cyclobenzaprine
-
-
BADD_D00546
Cyclobenzaprine hydrochloride
-
-
BADD_D00549
Cyclophosphamide
-
-
BADD_D00551
Cyclosporine
-
-
BADD_D00552
Cyproheptadine
-
-
BADD_D00553
Cyproheptadine hydrochloride
-
-
BADD_D00554
Cyproterone
-
-
BADD_D00555
Cyproterone acetate
-
-
BADD_D00560
Cytarabine
0.001066%
BADD_D00561
Cytarabine hydrochloride
-
-
BADD_D00564
Dabigatran etexilate
-
-
BADD_D00576
Danazol
0.004234%
BADD_D00580
Dapsone
0.004810%
BADD_D00581
Daptomycin
-
-
BADD_D00586
Darunavir
-
-
BADD_D00594
Deferasirox
0.052481%
BADD_D00595
Deferiprone
-
-
BADD_D00603
Delavirdine
-
-
BADD_D00604
Delavirdine mesylate
-
-
BADD_D00611
Desflurane
-
-
BADD_D00612
Desipramine
-
-
BADD_D00615
Desloratadine
0.002643%
BADD_D00621
Desvenlafaxine
0.000846%
BADD_D00623
Dexamethasone
-
-
BADD_D00628
Dexlansoprazole
0.000907%
BADD_D00648
Diazepam
0.000854%
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